[T#xxx]will identify a taxonomy entry, for example. Simply hit
ENTERafter typing in the ID to jump.
[HFG#xxx]Homologous Family Group
=), does not match (
!=), is similar (
~) or is smaller/larger (
>) to the value you provide.
contains the sequence browser. Sequence information on BioCatNet is classified in a hierarchical order containg six tabular groups ranging from sequences to superfamily groups. Several sequences may belong to a single protein. Proteins are grouped into families of homologous proteins (HFam) by sharing similar sequence patterns. Families of homologous proteins are grouped in superfamilies (SFam). According to similarities in sequence and function families of homologous proteins and superfamilies are summarized in extra groups (HFam groups and SFam groups).
The six hierarchical groups represent the six columns below the pie charts. By clicking on the name of a certain superfamily the user is guided to several families of homologous proteins and thereby gets access to various single sequence entries. Clicking on the name of a protein redirects to a page where different parts of information are collected including the annotated sequence, the biological source and (if available) information regarding structure and/ or function of the desired protein entry. Sequence information is parsed via NCBI accession numbers.
Protein structure is parsed from PDB entries into the BioCatNet system. Under the Structures bar PDB entries are available grouped by superfamilies, families of homologous proteins, proteins, sequences and source organisms.
One of BioCatNet's main features is the availability of data regarding biochemical functions such as experimental conditions or enzyme kinetics. Experimental scientists can submit their data after registration. For submission certain parameters are required in a virtual lab journal.
To enable consistent comparison of biochemical data certain information for the biocatalyst and the experimental conditions is mandatory. This includes the scale of the experiment (initial volume), a description of the reaction (including educts, products and their stoichiometry), detailed information on the biocatalyst(s), educts and products as well as description of buffer and solvents.
Optional information may include description of additive compounds, kinetics and experimental conditions (e.g. pH, temperature, pressure).